TARGETING STAT-3 SIGNALING PATHWAY IN CANCER FOR DEVELOPMENT OF NOVEL DRUGS: ADVANCEMENTS AND CHALLENGES


An Assessment of Satellite Radiance Data Assimilation in RMAPS

Due to the availability of observations and the effectiveness of bias correction, it is still a challenge to assimilate data from the polar orbit satellites into a limited-area and frequently updated model.This study assessed the initial application ultrastar dc hc550 of satellite radiance data from multiple platforms in the Rapid-refresh Multi-sca

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Dual Size-Dependent Effect of Fe3O4 Magnetic Nanoparticles Upon Interaction with Lysozyme Amyloid Fibrils: Disintegration and Adsorption

Nanomedicine compounds containing nanoparticles, such as iron oxides and gold, have been demonstrated to be effective in promoting different magnitudes of interaction with amyloid β fibrils, of which disintegrating or inhibiting effects are of great importance to treating fibrillary aggregation-induced neurological disorders such as Alzheimer&

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Dietary supplementation for female infertility: Recent advances in the nutritional therapy for premature ovarian insufficiency

Premature ovarian insufficiency (POI) ranks top in the reproductive disorders that may impair multiple functioning systems, reduce the quality of life and ultimately deprive ultrastar dc hc550 patients of their fertility among women.Symptoms can be partially alleviated by present hormone replacement therapy that cannot improve conception or decreas

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Assessing the use of blood microRNA expression patterns for predictive diagnosis of myxomatous mitral valve disease in dogs

BackgroundMyxomatous mitral valve disease (MMVD) is a common, acquired, and progressive canine heart disease.The presence of heart murmur and current cardiac biomarkers ventilationstejp are useful in MMVD cases but are not sufficiently discriminatory for staging an individual patient.ObjectivesThis study aimed to conduct a preliminary assessment of

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